• Western University

• PATHOL 2420

Module 3 A- Inflammation
Defintions
Acute - of short duration or occurring suddenly.
Cardinal signs of inflammation:
Rubor – redness
Tumor – swelling
Calor – heat
Dolor – pain
Functio laesa - loss of function or impaired function
Chemical mediators - a variety of chemicals secreted by various cells and from injured tissue
involved in the inflammatory response, e.g. histamine. Responsible for mediating vascular and
cellular responses in inflammation.
Chemotaxis - phenomenon that guides and attracts WBCs to the site of injury. Chemotactic
agents include some of the chemical mediators, antibodies, products from bacteria and dead
tissue.
Chronic - long-standing; occurring over a long period of time.
Exudate - fluid accumulation outside of a vessel; it has a high protein content and contains
various types of inflammatory cells.