• University of Minnesota-Twin Cities

• CHEM

Green Synthesis and Hydrogenation of a Di-substituted ChalconeBy: Rachel PetersonCourse: CHEM 2311 Sec 002TA: Casey CarpenterDate: April 11, 2019Purpose: The objective of this experiment is to follow green procedures to synthesize a di-substituted chalcone via an aldol condensation reaction of para-chlorobenzaldehyde and para-methoxyacetophenone and hydrogenate Chalcone 1. The major products of the aldolcondensation and hydrogenation reactions were purified by recrystallization.The initialhypothesis for the hydrogenation portion of this experiment is that of the three possiblefunctional groups that can be reduced by palladium, the chlorine and carbon-carbon double bondwill be reduced in the major product. Analysis tools of Mass Spectrometry, IR Spectroscopy,Melting Point Theory, and H NMR Spectroscopy are used to characterize the di-substitutedchalcone and determine the major product of hydrogenation. The analysis tools indicate whichfunctional groups of the di-substituted chalcone were reduced by palladium