University of California, Davis
BIS 104
BIS104 Final Exam, Form B 2 0. It is worth one point to properly fill out your student ID, name, and test form. Mark your test form down now. If we see you without a test form marked, you will be under suspicion of cheating. Please turn in any suspected cheaters near you. We will be discreet and anonymous. 1. You delete the first eigh
...[Show More]
BIS104 Final Exam, Form B 2 0. It is worth one point to properly fill out your student ID, name, and test form. Mark your test form down now. If we see you without a test form marked, you will be under suspicion of cheating. Please turn in any suspected cheaters near you. We will be discreet and anonymous. 1. You delete the first eight AND the last four amino acids of BiP. Where would you now predict the majority of BiP to now localize? A. Outside the cell B. The ER C. The cytoplasm D. The Golgi E. The nucleus 2. You isolate a mutation that disrupts the activity of the Ran GAP. In such a cell you notice a dramatic delay in the cell cycle that is most directly caused by a decrease in ________ that increases the time for ___________. A. nuclear import; nuclear envelope breakdown B. microtubule dynamics; chromosome alignment C. microtubule dynamics; cytokinesis D. nuclear import; chromosome alignment E. mitotic checkpoint; nuclear envelope breakdown 3. Which of the following does the estrogen receptor contain? A. A DNA-binding domain B. A SH2-binding domain C. A GEF D. An NPSY E. Exactly one trans-membrane domain. 4. An infant, that is unable to acquire antibodies properly from his mother's breast milk, is born. Tests determine that the infant makes receptors for the antibodies, but they are mutant; the NPAY in the wild-type receptor is mutated to APAY in the mutant receptor. Based on this mutation you predict this protein will not be __________ and therefore fail to _________. A. phosphorylated; bind to SH3 domains B. glycocylated; exit the ER C. glycocylated; be internalized D. incorporated into endocytotic vesicles; bind to adaptor proteins E. phosphorylated; bind to SH2 domains 5. You add a KDEL sequence to the C-terminus of the wild-type antibody receptor discussed in the question above. Where would you now find the bulk of this protein? A. In the cytosol B. In the ER membrane C. In the Golgi membrane D. In the membrane of the lysosome E. In the plasma membrane
[Show Less]
-preview.jpeg)
-preview.jpeg)
-preview.jpeg)
